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Start your Research cursus with us

Practical teaching introduction to Research

A program of training has a practice in the experimental approaches being a member of the level internship 4th year of university is proposed to prepare the students for their entrance to the program of Master 2. This internship must be completed by EU fundamental organized on the faculty and in Medicine. The laboratory welcomes students of the Mention BCPP Speciality Biomineralization, Morphogenesis and Inflammatory Pathologies and other specialities of Master’s degree

Master's degree BCPP

Research Speciality ``biomineralization, morphogenesis and inflammatory pathologies`` (BMPI)

The speciality” biomineralization, morphogenesis and inflammatory pathologies ” is intended for the research. Its contents are adapted to the themes of oral and osteo-articular health. It is a place of exchange between students and researchers, odontologists, doctors and scientists with a national and international participation. The theoretical contents (6 EU) give a global vision of skeleton tissues, stem cells in the biomineralization, the inflammatory processes and the cellular biotherapics with bio-active materials. The internshipsare a personal coverage(care), redrawn by a report, of a scientific question in laboratories of excellent welcome (reception). It is advised (recommended) to get in touch with the speciality to pilot the choice of its research team in connection with objectives or personal affinities (genetics, pathology, growth and development, materials, tissular engineering, immunology). The oral tests which one in English and written take place at the end of every half-year.

Director of the program: Pr Ariane BERDAL

secretarial office: Shu-Chiung.Kovats@crc.jussieu.fr

The speciality “Oral Applied Pathophysiology” has for objective to form by the clinical approach of the students stemming from diverse formations of the sector health, including the veterinarians. In term of public health, needs evolve, requiring a care of specific sick, in particular people disabled or reached (affected) by rare diseases. So there was a creation of specialized centers and the necessity for the odontologists to deepen their skills. We also observe a therapeutic sophistication associated with the evolutions of the research in odontology (use of growth factors, dental implants, etc.).The speciality OAP is organized allowing the student to deepen its knowledge in one of the fields disciplinary of the Odontology:

-Periodontology

-Endodontics

-Pediatric Dentistry and Rare Diseases

The students have to follow clinical clerkship corresponding to the discipline of orientation, in the first and second year of Master’s degree. The student’s selection is made on audition with a selection committee Master to 4th year of university.

Director of the program:
Paris Diderot:

Pr Muriel De La Dure – Molla  murielmolla@gmail.com
Paris Descartes:
Pr Bruno Gogly    bruno.gogly@parisdescartes.fr

Master BCPP

Speciality professional «oral applied pathophysiology» (OAP)

Dental School Garancière (University Paris Diderot - Paris 7)

Pr Stéphane SIMON   stephane.simon@u-paris.fr

Recurrent health crises (asbestos, dioxin, magnetic fields, bisphenol A,…) clearly highlight the close relations between man and his environment and the sometimes dramatic consequences of a poor health risk assessment. The development of new technologies and innovations in industry and research (e.g. nanotechnologies) mean that new substances are constantly being generated. Improving knowledge leads to the identification of emerging risks (e.g. endocrine disrupters) and the question of the effects of environments on health (general environment, professional environment, food) is a major concern. In order to meet the challenges related to human health, while respecting the environment, it is essential that education be provided that takes into account current toxicological and safety concerns (air and water quality, toxicological safety of foodstuffs, safety of working environments).

The “Toxicology, Environment, Health” (TES) course aims to train students from different origins (biologists, doctors, pharmacists, veterinarians, agronomists, environmental and chemical engineers as well as actors from the professional world. Thanks to this multidisciplinary training, the graduate will have solid scientific knowledge on the cellular and molecular mechanisms of action of environmental pollutants and their physio-pathological consequences, on the exposure modalities according to the considered environments (general and professional) and good bases in epidemiology and risk assessment.

He will also have professional skills (bibliographic analysis and synthesis, written and oral communication of experimental results, team work, ability to debate).

 

Sylvie Babajko’s team welcomes master students from the Master 2 « Toxicology, Environment and Hearth »

sylvie.babajko@inserm.fr

Master 2

Toxicology Enviroment and Health | Paris-Descarted University

We stand out!

EXPERIMENTAL APPROACH

Methods for proteins visualization in dental mineralized tissues.
Hotton. D, Berdal. A and Bolanos. A.
Odontogenesis Protocols Book
Springerlag Editor.2019. 1922; 173-180

In situ Hybridization in mineralized tissues: the added value of LNA probes for RNA detection
Lignon. G, Hotton.D, Berdal. A and Bolanos. A.
Odontogenesis Protocols Book.
Springerlag Editor. 2019.1922; 181-190

RECENT PUBLICATIONS

Gama A, Maman L, Vargas-Franco JW, Omar R, Royer BB, Yagita H, Babajko S, Berdal A, Acevedo AC, Heymann D, Lézot F, Castaneda B. Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth. J Clin Med.2020;9(4). https://doi.org/10.3390/jcm9040898

Abdal-Hay A, Thattaruparambil Raveendran N, Fournier B, Ivanovski S. Fabrication of Biocompatible and Bioabsorbable Polycaprolactone/ Magnesium Hydroxide 3D Printed Scaffolds: Degradation and in vitro Osteoblasts Interactions. Composites Part B: Engineering. 2020, in press

Babajko S, Gayrard V, Houari S, Thu Bui A, Barouki R, Niederreither K, Fini JB, Dursun E, Coumoul X. `{`Oral cavity as a target and a marker of environmental exposures: developmental dental defects`}`. Med Sci (Paris). 2020;36(3):225-230. https://doi.org/10.1051/medsci/2020024

Babajko S, Lescaille G, Radoï L, Thu Bui A, Baaroun V, Boyer E, Delbosc S,Chardin H, Barouki R, Coumoul X. `{`Oral cavity as a target and a marker ofenvironmental exposures: diseases diagnosed during adulthood`}`. Med Sci (Paris).2020;36(3):231-234. https://doi.org/10.1051/medsci/2020025
Gama A, Vargas-Franco JW, Sánchez Mesa DC, Restrepo Bedoya E, Amiaud J, Babajko S, Berdal A, Acevedo AC, Heymann D, Lézot F, Castaneda B. Origins of Alterations to Rankl Null Mutant Mouse Dental Root Development. Int J Mol Sci.2020;21(6).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139335/

Merzoug-Larabi M, Youssef I, Bui AT, Legay C, Loiodice S, Lognon S, Babajko S, Ricort JM. Protein Kinase D1 (PKD1) Is a New Functional Non-Genomic Target of Bisphenol A in Breast Cancer Cells. Front Pharmacol. 2020.10:1683.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006487/

2019
Youssef I, Ricort JM. Deciphering the Role of Protein Kinase D1 (PKD1) in Cellular Proliferation. Mol Cancer Res. 2019;17(10):1961-1974. https://mcr.aacrjournals.org/content/17/10/1961.long

Chekroun M, Cherifi H, Fournier B, Gaultier F, Sitbon IY, Ferre FC, Gogly B. 2019. Oral manifestations of sickle cell disease. Br Dent J. 226(1):27-31. doi: 10.1038/sj.bdj.2019.4.

de La Dure-Molla M, Fournier BP, Manzanares MC, Acevedo AC, Hennekam RC, Friedlander L, Boy-Lefèvre ML, Kerner S, Toupenay S, Garrec P, Vi-Fane B, Felizardo R, Berteretche MV, Jordan L, Ferré F, Clauss F, Jung S, de Chalendar M, Troester S, Kawczynski M, Chaloyard J; International Group of Dental Nomenclature, Manière MC, Berdal A, Bloch-Zupan A. Elements of morphology: Standard terminology for the teeth and classifying genetic dental disorders. Am J Med Genet A. 2019;179(10):1913-1981. https://doi.org/10.1002/ajmg.a.61316

Friedlander L, Berdal A, Boizeau P, Licht BA, Manière MC, Picard A, Azzis O, Vazquez MP, Alberti C, Molla MD. Oral health related quality of life of children and adolescents affected by rare orofacial diseases: a questionnaire-based cohort study. Orphanet J Rare Dis. 2019;14(1):124. doi: 10.1186/s13023-019-1109-2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549379/

Gama A, Perea L, Yepes C, Betancur JJ, Vargas J, Amiaud J, Babajko S, Lezot F, Castaneda B. `{`Effects of post-natal inhibition of RANKL on molar eruption and root formation in C57BL/6 mice`}`. Orthod Fr. 2019;90(1):55-63. https://doi.org/10.1051/orthodfr/2019008

Houari S, Picard E, Wurtz T, Vennat E, Roubier N, Wu TD, Guerquin-Kern JL, Duttine M, Thuy TT, Berdal A, Babajko S. Disrupted Iron Storage in Dental Fluorosis. J Dent Res. 2019;98(9):994-1001. doi: 10.1177/0022034519855650. https://doi.org/10.1177/0022034519855650

Jordan L, Beydon N, Razanamihaja N, Garrec P, Carra MC, Fournier BP, Vi-Fane B, Kerner S, Felizardo R, Boy-Lefèvre ML, De La Dure-Molla M. Translation and cross-cultural validation of the French version of the Sleep-Related Breathing Disorder scale of the Pediatric Sleep Questionnaire. Sleep Med. 2019;58:123-129. https://doi.org/10.1016/j.sleep.2019.02.021

Korah L, Amri N, Bugueno IM, Hotton D, Tenenbaum H, Huck O, Berdal A, Davideau JL. Experimental periodontitis in Msx2 mutant mice induces alveolar bone necrosis. J Periodontol. 2019. https://doi.org/10.1002/JPER.16-0435

Perea-Gomez A, Cases O, Lelièvre V, Pulina MV, Collignon J, Hadjantonakis AK, Kozyraki R. Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse. Sci Rep. 2019;9(1):10168. doi: 10.1038/s41598-019-46559-0https://www.nature.com/articles/s41598-019-46559-0

Taïhi I, Nassif A, Isaac J, Fournier BP, Ferré F. Head to Knee: Cranial Neural Crest-Derived Cells as Promising Candidates for Human Cartilage Repair. Stem Cells Int. 2019;2019:9310318. doi: 10.1155/2019/9310318https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350557/

Vutipongsatorn K, Nagaoka N, Yokoi T, Yoshida T, Kamoi K, Horie S, Uramoto K, Hirata A, Occelli LM, Petersen-Jones SM, Montiani-Ferreira F, Cases O, Kozyraki R, Jonas JB, Ohno-Matsui K.
Correlations Between Experimental Myopia Models And Human Pathologic Myopia. Retina. 2019;39(4):621-635. doi: 10.1097/IAE.0000000000002426
https://journals.lww.com/retinajournal/Abstract/2019/04000/CORRELATIONS_BETWEEN_EXPERIMENTAL_MYOPIA_MODELS.1.aspx

WHAT HAPPENED TO THE FORMER THESIS STUDENTS

Current Positions

MEETING PARTICIPATION

IADR/PER General Session & Exhibition, July 25-28 , 2018 London, England

A.Berdal
Oral presentations: The Paradoxical Phenotype in FAM20A Gene Mutations Amelogenesis Imperfecta and Ectopic Mineralization in Soft Tissues
A Debate in Oral Pathophysiology: Would Osteoblasts be Different in Jaws and Long Bones

A.Bolanos
Oral Presentation: Biomimetics Properties Analysis of a Brushite-based Material for Pulp Healing

F.Beres
Poster Presentation: Development of a New Biomimetic Material for Bone Regeneration

Academic recognition

Join one of the most recognized universities world wide

Practical Teaching

Organisation of a ``Research Initiation`` value unit at the Faculty of Dentistry (Garanciere) of the Paris Diderot University.
These courses are intended for undergraduate students.
D.Hotton and A.Bolanos